Best Treatment of type 1 diabetes
The best treatment for Type 1 diabetes, according to the "American Diabetes Association Releases Standards of Care in Diabetes—2025," includes the following recommendations:
1. Insulin Therapy: Most adults with Type 1 diabetes should be treated with continuous subcutaneous insulin infusion (insulin pump therapy) or multiple daily injections of prandial (injected or inhaled) and basal insulin. Insulin analogs are preferred to minimize the risk of hypoglycemia[1][2].
2. Continuous Glucose Monitoring (CGM): Early use of CGM is recommended to improve glycemic outcomes and quality of life while minimizing hypoglycemia[3].
3. Automated Insulin Delivery Systems: Automated insulin delivery (AID) systems should be offered to all adults with Type 1 diabetes as they can improve glycemic control and reduce the risk of hypoglycemia[1][4].
4. Education: Individuals should receive education on how to adjust mealtime insulin doses to account for carbohydrate intake, as well as how to modify doses based on concurrent glycemia and trends[5][6].
5. Regular Reevaluation: The insulin treatment plan should be reevaluated and adjusted regularly to ensure that individualized glycemic goals are met, taking into consideration factors such as lifestyle, health status, and preferences[7].
6. Additional Medications: Noninsulin medications like pramlintide (an amylin analog) and some glucagon-like peptide 1 receptor agonists (GLP-1 RAs) have been studied as adjuncts to insulin therapy to help improve glycemic control and support weight management[2][2]. However, caution is advised with the use of sodium-glucose cotransporter 2 (SGLT2) inhibitors due to their association with an increased risk of diabetic ketoacidosis (DKA)[6].
7. Nutrition and Physical Activity: Individualized medical nutrition therapy is essential, focusing on carbohydrate intake management and a balanced diet. Physical activity should also be encouraged[8].
Implementing these strategies can help optimize management and improve the quality of life for individuals living with Type 1 diabetes.