Diagnostic Criteria for Diabetes (2025 ADA Standards)
Diagnosis of Diabetes:
Diabetes can be diagnosed through one of the following criteria, which must be confirmed by repeat testing unless clinical symptoms are present:
1.
A1C: ≥ 6.5% (≥ 48 mmol/mol)
- The test must be performed in a laboratory using an NGSP-certified method.
2.
Fasting Plasma Glucose (FPG): ≥ 126 mg/dL (≥ 7.0 mmol/L)
- Fasting is defined as no caloric intake for at least 8 hours.
3.
2-Hour Plasma Glucose: ≥ 200 mg/dL (≥ 11.1 mmol/L)
- This should be conducted during a 75-g Oral Glucose Tolerance Test (OGTT).
4.
Random Plasma Glucose: ≥ 200 mg/dL (≥ 11.1 mmol/L)
- This is applicable in individuals with classic symptoms of hyperglycemia or hyperglycemic crisis.
In the absence of unequivocal hyperglycemia (such as hyperglycemic crises), diagnosis requires confirmatory testing, which can include any of the aforementioned tests done on separate occasions
[1][2].
Prediabetes Diagnosis:
For prediabetes, the following criteria apply:
- A1C: 5.7% – 6.4% (39 – 47 mmol/mol)
- FPG: 100 – 125 mg/dL (5.6 – 6.9 mmol/L; classified as Impaired Fasting Glucose - IFG)
- 2-Hour Plasma Glucose: 140 – 199 mg/dL (7.8 – 11.0 mmol/L during a 75-g OGTT; classified as Impaired Glucose Tolerance - IGT)[3][4].
Summary
This information serves as critical guidance for healthcare professionals in diagnosing diabetes and prediabetes according to the 2025 American Diabetes Association Standards of Care
[5][6].
References
- Source: 4:5
- Source: 4:1
- Source: 4:11
- Source: 4:3
- Source: 4:2
- Source: 4:4
