The management of type 1 diabetes centers around insulin therapy, which is essential due to the absence of insulin production in these patients. Here are the key treatment strategies based on the "American Diabetes Association Standards of Care in Diabetes—2025":

1. Insulin Administration:

• The preferred method for managing type 1 diabetes is through a regimen of continuous subcutaneous insulin infusion (CSII) via insulin pumps or multiple daily injections (MDI) of prandial (mealtime) and basal insulin^[1][2].

• Insulin analogs are favored over regular human insulins to minimize the risk of hypoglycemia. This includes using rapid-acting and long-acting insulin analogs^[1][2].

2. Continuous Glucose Monitoring (CGM):

• Early initiation of continuous glucose monitoring is recommended to improve glycemic control and quality of life while reducing hypoglycemia events^[1][3].

3. Automated Insulin Delivery Systems:

• Automated insulin delivery systems (AID) should be offered to all individuals with type 1 diabetes, as they can improve glycemic control and reduce hypoglycemic incidents^[3][1].

4. Education and Self-Management:

• Patients should receive education on matching mealtime insulin doses to carbohydrate intake and managing insulin doses based on concurrent blood glucose levels. This education should be revisited regularly^[1][4].

5. Meal Planning and Nutrition:

• Individualized medical nutrition therapy is crucial, focusing on carbohydrate counting and monitoring the impact of dietary choices on blood glucose^[5].

6. Adjunctive Therapies:

• Some adjunctive therapies like pramlintide can provide modest reductions in A1C and weight but should be carefully considered due to their effects^[6][5].

• Recent investigations into GLP-1 receptor agonists and SGLT2 inhibitors for adjunctive treatment in type 1 diabetes are ongoing, but use carries risks such as diabetic ketoacidosis (DKA)^[6][7].

7. Regular Monitoring and Adjustments:

• Insulin plans should be reviewed and adjusted every 3-6 months, ensuring alignment with the individual's goals and medical needs^[1][2].

For further information, consult the detailed guidelines in the "American Diabetes Association Standards of Care in Diabetes—2025"^[1].

References

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2. Source: 4:16
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7. Source: 4:19